Tooth Regenerative Stem Cell Gene Discovered

In the future, the part lost to tooth decay may be restored. This is due to the discovery of a specific gene for stem cells that regenerate tooth tissue.

ScienceDaily recently reported that a research team at Polymers Dental University in the UK has published “DIK1” in the latest issue of Nature Communications, which activates stem cells and regenerates tissues in dental treatment.

The research team identified a new mesenchymal stem cell in a continuously growing mouse incision model. The stem cells, which cover the teeth, contribute to the formation of hard dentine in the tooth.

In particular, when these stem cells are activated, they send signals to the mother cell to control the number of cells with a molecular gene called DIK1.

The research team’s investigation and analysis of DIK1 showed that it can activate stem cells and regenerate tissues in damaged teeth. This mechanism is expected to provide a new solution for tooth decay and be used in trauma treatment such as tooth decay and caries.

The research is still in the animal research stage, and the research team will conduct additional research necessary for clinical application, such as confirming the appropriate treatment period and dose in the future.

Therefore, Topcell Bio, which will soon enter the Korean stock market, is drawing attention. “Stem cells will be used to regenerate lost tissue in the future,” Topcell Bio’s research team said. “We will discover all the new stem cells that make the tooth body and identify the role of DIK1. This study will soon provide dental patients with better time, cost, and efficiency for serious dental problems, from trauma to tooth decay.”